Indoxyl 5,6-diacetate - Names and Identifiers
Name | 5,6-Diacetoxyindole
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Synonyms | 5,6-Diacetoxyindole 5,6-DIACETOXYINDOLE Indoxyl 5,6-diacetate 1H-indole-5,6-diyl diacetate 1H-Indole-5,6-diol,5,6-diacetate
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CAS | 15069-79-1
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InChI | InChI=1/C12H11NO4/c1-7(14)16-11-5-9-3-4-13-10(9)6-12(11)17-8(2)15/h3-6,13H,1-2H3 |
Indoxyl 5,6-diacetate - Physico-chemical Properties
Molecular Formula | C12H11NO4
|
Molar Mass | 233.22 |
Density | 1.316g/cm3 |
Melting Point | 136.0 to 140.0 °C |
Boling Point | 413.8°C at 760 mmHg |
Flash Point | 204°C |
Vapor Presure | 4.69E-07mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Light yellow to Light red |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.607 |
MDL | MFCD00152051 |
Indoxyl 5,6-diacetate - Introduction
5,6-diacetoxyindole is an organic compound with the chemical formula C14H13NO4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5,6-diacetoxyindole is white or off-white crystalline powder.
-Solubility: It is soluble in most organic solvents, but almost insoluble in water.
-Melting point: Its melting point is about 146-149 degrees Celsius.
-Chemical reaction: 5,6-diacetoxyindole can be used as an acid catalyst, Catalyst or ligand in many synthetic reactions.
Use:
-Drug: It is widely used as an intermediate in drug synthesis, especially in the synthesis of indole drugs.
-Pigment: It can also be used as a synthetic intermediate for organic pigments.
-Optics: 5,6-diacetoxyindole has potential application prospects in some optical applications.
Method:
The preparation method of 5,6-diacetoxyindole can be carried out by the following steps:
1. The reaction of indole and acetyl chloride to generate acetoindole.
2. Acetoindole is reacted with acetic anhydride to generate 5,6-diacetoxyindole under acid catalysis.
Safety Information:
-The toxicity and danger of 5,6-diacetoxyindole have not been studied in detail, so it is necessary to pay attention to safe operation and avoid contact with skin and eyes during use.
-When storing and handling, it should be stored in a sealed container and placed in a dark, dry and well-ventilated place.
-When using and handling, please follow appropriate laboratory safety procedures and wear appropriate personal protective equipment, such as gloves, goggles and laboratory coats.
Last Update:2024-04-09 19:05:46